Product Info Summary
SKU: | M01304 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Mouse |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-N-CoR NCOR1 Monoclonal Antibody
SKU/Catalog Number
M01304
Size
100ul
Form
Liquid
Description
Boster Bio Anti-N-CoR NCOR1 Monoclonal Antibody catalog # M01304. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-N-CoR NCOR1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01304)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
7A7A9
Isotype
IgG
Immunogen
Purified recombinant fragment of N-CoR (aa1-192) expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
M01304 is reactive to NCOR1 in Human
Applications
M01304 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
270.21kDa
Background of NCOR1
TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of NCOR1 using Anti-N-CoR NCOR1 Monoclonal Antibody (M01304).
Immunohistochemistry (IHC) analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right)Click image to see more details
Figure 1. Western blotting validation for Anti-N-CoR NCOR1 Monoclonal Antibody M01304
Western Blot (WB) analysis using N-CoR Monoclonal Antibody against truncated Trx-N-CoR recombinant protein (1).Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For NCOR1 (Source: Uniprot.org, NCBI)
Gene Name
NCOR1
Full Name
Nuclear receptor corepressor 1
Weight
270.21kDa
Superfamily
N-CoR nuclear receptor corepressors family
Alternative Names
hN-CoR; KIAA1047; KIAA1047N-CoR1; MGC104216; N-CoR; NCOR1; N-CoRhCIT529I10; nuclear receptor corepressor 1; nuclear receptor co-repressor 1; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC1 NCOR1 N-CoR, N-CoR1, PPP1R109, TRAC1, hN-CoR nuclear receptor corepressor 1 nuclear receptor corepressor 1|protein phosphatase 1, regulatory subunit 109|thyroid hormone- and retinoic acid receptor-associated corepressor 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NCOR1, check out the NCOR1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NCOR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-N-CoR NCOR1 Monoclonal Antibody (M01304)
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No publications found for M01304
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Customer Reviews
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