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Product Info Summary
| SKU: | A06595 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Neuroligin-2 NLGN2 Antibody
View all Neuroligin 2/NLGN2 Antibodies
SKU/Catalog Number
A06595
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Neuroligin-2 NLGN2 Antibody (Catalog # A06595). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
NLGN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Neuroligin-2 NLGN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06595)
Host
Rabbit
Contents
NLGN2 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2. The immunogen is located within amino acids 630 - 680 of NLGN2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
NLGN2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. NLGN2 antibody is predicted to not cross-react with other members of the NLGN protein family.
Reactive Species
A06595 is reactive to NLGN2 in Human, Mouse, Rat
Applications
A06595 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
90.82kDa
Background of Neuroligin 2/NLGN2
Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NLGN2 antibody can be used for detection of NLGN2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of NLGN2 in rat brain tissue lysate with NLGN2 antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of NLGN2 in mouse brain tissue with NLGN2 antibody at 5 μg/ml.
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Immunofluorescence of NLGN2 in mouse brain tissue with NLGN2 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For NLGN2 (Source: Uniprot.org, NCBI)
Gene Name
NLGN2
Full Name
Neuroligin-2
Weight
90.82kDa
Superfamily
type-B carboxylesterase/lipase family
Alternative Names
EC 3.1.1; EC 3.1.1.1; KIAA1366neuroligin-2; Neuroligin 2; NLGN2 NLGN2 neuroligin 2 neuroligin-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NLGN2, check out the NLGN2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NLGN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Neuroligin-2 NLGN2 Antibody (A06595)
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No publications found for A06595
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