Product Info Summary
SKU: | A09888-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Nrf3 (D530) NFE2L3 Antibody
SKU/Catalog Number
A09888-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Nrf3 (D530) NFE2L3 Antibody catalog # A09888-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Nrf3 (D530) NFE2L3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09888-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human YOD1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09888-1 is reactive to NFE2L3 in Human, Mouse, Rat
Applications
A09888-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
76.154kDa
Background of NRF3
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.
Ota T., Nat. Genet. 36:40-45(2004).
Gregory S.G., Nature 441:315-321(2006).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For NFE2L3 (Source: Uniprot.org, NCBI)
Gene Name
NFE2L3
Full Name
Nuclear factor erythroid 2-related factor 3
Weight
76.154kDa
Superfamily
bZIP family
Alternative Names
NF-E2-related factor 3; NFE2-related factor 3; Nrf3; NRF3nuclear factor erythroid 2-related factor 3; nuclear factor (erythroid-derived 2)-like 3; Nuclear factor, erythroid derived 2, like 3; nuclear factor-erythroid 2 p45-related factor 3; nuclear factor-erythroid 2-related factor 3 NFE2L3 NRF3 nuclear factor, erythroid 2 like 3 nuclear factor erythroid 2-related factor 3|NF-E2-related factor 3|NFE2-related factor 3|nuclear factor, erythroid derived 2, like 3|nuclear factor-erythroid 2 p45-related factor 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NFE2L3, check out the NFE2L3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NFE2L3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Nrf3 (D530) NFE2L3 Antibody (A09888-1)
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No publications found for A09888-1
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