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Product Info Summary
| SKU: | A07497 |
|---|---|
| Size: | 150 ul |
| Reactive Species: | Rat |
| Host: | Rabbit |
| Application: | IHC, ICC |
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Product info
Product Name
Anti-P2X1 P2RX1 Antibody
View all P2X1/P2RX1 Antibodies
SKU/Catalog Number
A07497
Size
150 ul
Form
Liquid
Description
Boster Bio Anti-P2X1 P2RX1 Antibody (Catalog# A07497). Tested in ICC, IHC applications. This antibody reacts with Rat.
Storage & Handling
Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-P2X1 P2RX1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07497)
Host
Rabbit
Contents
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Clonality
Polyclonal
Clone Number
10C3
Isotype
Rabbit IgG
Immunogen
309-324 GAEGGAGGADGQGAGP
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Detects ~20kDa. Does not cross-react with αB-crystallin, βL-crystallin, ΒH- crystallin, γ-crystallin, HSP25, HSP27 or HSP47 proteins.
Reactive Species
A07497 is reactive to P2RX1 in Rat
Applications
A07497 is guaranteed for IHC, ICC Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
44.98kDa
Background of P2X1/P2RX1
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994). The GluR1 subunit is widely expressed throughout the nervous system. Phosphorylation of Ser-845 on GluR1 is thought to be mediated by PKA and phosphorylation of this site increases the conductance of the AMPAR (Roche et al., 1996; Banke et al., 2000). In addition, phosphorylation of this site has been linked to synaptic plasticity as well as learning and memory (Lee at al., 2003; Esteban at al., 2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ICC 1: 5-10,000
Validation Images & Assay Conditions
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Figure 1. Validation data of P2RX1 using Anti-P2X1 P2RX1 Antibody (A07497).
Protein Target Info & Infographic
Gene/Protein Information For P2RX1 (Source: Uniprot.org, NCBI)
Gene Name
P2RX1
Full Name
P2X purinoceptor 1
Weight
44.98kDa
Superfamily
P2X receptor family
Alternative Names
ATP receptor; P2RX1; P2X purinoceptor 1; P2X receptor, subunit 1; P2X1; P2X1P2X1 receptor; P2XMR; purinergic receptor P2X, ligand-gated ion channel, 1; Purinergic receptor P2RX1 P2X1 purinergic receptor P2X 1 P2X purinoceptor 1|ATP receptor|P2X receptor, subunit 1|P2X1 receptor|purinergic receptor P2X, ligand gated ion channel, 1|purinergic receptor P2X1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on P2RX1, check out the P2RX1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for P2RX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-P2X1 P2RX1 Antibody (A07497)
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No publications found for A07497
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Customer Reviews
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