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Product Info Summary
| SKU: | A04425 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-PMS1 protein homolog 1 PMS1 Antibody
SKU/Catalog Number
A04425
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PMS1 protein homolog 1 PMS1 Antibody catalog # A04425. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PMS1 protein homolog 1 PMS1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04425)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04425 is reactive to PMS1 in Human, Mouse, Rat
Applications
A04425 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
105.83kDa
Background of PMS1
Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-PMS1 protein homolog 1 PMS1 Antibody A04425
Western blot (WB) analysis of PMS1 polyclonal antibody at 1:500 dilutionLane1:Hela cell lysate
Lane2:Raw264.7 cell lysate
Lane3:PC12 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For PMS1 (Source: Uniprot.org, NCBI)
Gene Name
PMS1
Full Name
PMS1 protein homolog 1
Weight
105.83kDa
Superfamily
DNA mismatch repair MutL/HexB family
Alternative Names
DKFZp781M0253; FLJ98259; HNPCC3; hPMS1; human homolog of yeast mutL; mismatch repair gene PMSL1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMS1 protein homolog 1; PMSL1DNA mismatch repair protein PMS1; postmeiotic segregation increased (S. cerevisiae) 1; rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarcoma antigen MU-RMS-40.10E PMS1 HNPCC3, MLH2, PMSL1, hPMS1 PMS1 homolog 1, mismatch repair system component PMS1 protein homolog 1|DNA mismatch repair protein PMS1|PMS1 postmeiotic segregation increased 1|human homolog of yeast mutL|mismatch repair gene PMSL1|rhabdomyosarcoma antigen MU-RMS-40.10B|rhabdomyosarcoma antigen MU-RMS-40.10E
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PMS1, check out the PMS1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PMS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PMS1 protein homolog 1 PMS1 Antibody (A04425)
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No publications found for A04425
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