Product Info Summary
SKU: | A07025-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-POLR1C Antibody
SKU/Catalog Number
A07025-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-POLR1C Antibody catalog # A07025-1. Tested in WB,IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-POLR1C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07025-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human TSEN54.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07025-1 is reactive to POLR1C in Human
Applications
A07025-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
39.25kDa
Background of POLR1C
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Zody M.C., Nature 440:1045-1049(2006).
Paushkin S.V., Cell 117:311-321(2004).
Ota T., Nat. Genet. 36:40-45(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For POLR1C (Source: Uniprot.org, NCBI)
Gene Name
POLR1C
Full Name
DNA-directed RNA polymerases I and III subunit RPAC1
Weight
39.25kDa
Superfamily
archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family
Alternative Names
AC40; DNA-directed RNA polymerase I subunit C; DNA-directed RNA polymerases I and III 40 kDa polypeptide; POLR1E; polymerase (RNA) I polypeptide C, 30kDa; RNA polymerase I subunit; RPA39RNA polymerases I and III subunit AC1; RPA40TCS3; RPA5RPAC1DNA-directed RNA polymerases I and III subunit RPAC1; RPC40 POLR1C AC40, HLD11, RPA39, RPA40, RPA5, RPAC1, RPC40, TCS3 RNA polymerase I and III subunit C DNA-directed RNA polymerases I and III subunit RPAC1|DNA-directed RNA polymerase I subunit C|DNA-directed RNA polymerases I and III 40 kDa polypeptide|RNA polymerase I subunit C|RNA polymerases I and III subunit AC1|polymerase (RNA) I polypeptide C, 30kDa|polymerase (RNA) I subunit C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on POLR1C, check out the POLR1C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for POLR1C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-POLR1C Antibody (A07025-1)
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No publications found for A07025-1
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