Anti-SET Monoclonal Antibody

Product Name

Anti-SET Monoclonal Antibody

View all SET Antibodies

SKU/Catalog Number

M02211

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-SET Monoclonal Antibody catalog # M02211. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SET Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02211)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

AEEO-19

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human SET Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M02211 is reactive to SET in Human, Mouse, Rat

Applications

M02211 is guaranteed for Flow Cytometry, IP, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

80 kDa

Calculated molecular weight

33.489kDa

Background of SET

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:100-1:500
IP 1:30
FC 1:20

Validation Images & Assay Conditions

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Western blot analysis of SET expression in HepG2 cell lysate.

Gene/Protein Information For SET (Source: Uniprot.org, NCBI)

Alternative Names

2PP2A; HLA-DR-associated protein II; I2PP2A; I-2PP2A; IGAAD; Inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; IPP2A2; PHAPIITAF-I; Phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor; protein SET; SET nuclear oncogene; SET translocation (myeloid leukemia-associated); TAF-IBETA; Template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor SET 2PP2A, I2PP2A, IGAAD, IPP2A2, MRD58, PHAPII, TAF-I, TAF-IBETA SET nuclear proto-oncogene protein SET|HLA-DR-associated protein II|SET nuclear oncogene|SET translocation (myeloid leukemia-associated)|Template-Activating Factor-I, chromatin remodelling factor|chromatin remodelling factor|inhibitor of granzyme A-activated DNase|inhibitor-2 of protein phosphatase-2A|phosphatase 2A inhibitor I2PP2A|protein phosphatase type 2A inhibitor

For more info on SET, check out the SET Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SET: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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