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Product Info Summary
| SKU: | A02622 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-SLC11A2 Antibody
View all NRAMP2/SLC11A2/DMT1 Antibodies
SKU/Catalog Number
A02622
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SLC11A2 Antibody catalog # A02622. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SLC11A2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02622)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human SLC11A2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02622 is reactive to SLC11A2 in Human, Mouse, Rat
Applications
A02622 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
62.266kDa
Background of NRAMP2/SLC11A2/DMT1
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000-1:2000
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Western blot analysis of extract of various cells, using SLC11A2 antibody.
Protein Target Info & Infographic
Gene/Protein Information For SLC11A2 (Source: Uniprot.org, NCBI)
Gene Name
SLC11A2
Full Name
Natural resistance-associated macrophage protein 2
Weight
62.266kDa
Superfamily
NRAMP family
Alternative Names
DCT1; DCT1NRAMP 2; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; DMT1FLJ37416; member 2; NRAMP2; NRAMP2natural resistance-associated macrophage protein 2; SLC11A2; solute carrier family 11 (proton-coupled divalent metal ion transporters) SLC11A2 AHMIO1, DCT1, DMT1, NRAMP2 solute carrier family 11 member 2 natural resistance-associated macrophage protein 2|DMT-1|NRAMP 2|divalent cation transporter 1|solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2|solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC11A2, check out the SLC11A2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC11A2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLC11A2 Antibody (A02622)
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No publications found for A02622
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Customer Reviews
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