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Product Info Summary
| SKU: | M01945 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-SLC22A1 Rabbit Monoclonal Antibody
SKU/Catalog Number
M01945
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SLC22A1 Rabbit Monoclonal Antibody catalog # M01945. Tested in IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SLC22A1 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01945)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Monoclonal
Clone Number
2D10F4
Isotype
IgG
Immunogen
Synthesized peptide derived from human OCT1 Monoclonal Antibody
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01945 is reactive to SLC22A1 in Human
Applications
M01945 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
61.154kDa
Background of SLC22A1
Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-p 1:50-200, WB 1:500-2000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For SLC22A1 (Source: Uniprot.org, NCBI)
Gene Name
SLC22A1
Full Name
Solute carrier family 22 member 1
Weight
61.154kDa
Superfamily
major facilitator (TC 2.A.1) superfamily
Alternative Names
hOCT1; OCT1; oct1_cds; OCT1solute carrier family 22 member 1; Organic cation transporter 1; SLC22A1; solute carrier family 22 (organic cation transporter), member 1 SLC22A1 HOCT1, OCT1, oct1_cds solute carrier family 22 member 1 solute carrier family 22 member 1|organic cation transporter 1|solute carrier family 22 (organic cation transporter), member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC22A1, check out the SLC22A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC22A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLC22A1 Rabbit Monoclonal Antibody (M01945)
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No publications found for M01945
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