Anti-Somatostatin Receptor 2/SSTR2 Antibody

Somatostatin R2/SSTR2 antibody

Boster Bio Anti-Somatostatin Receptor 2/SSTR2 Antibody catalog # PA1694. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 2 publication(s).

Product Info Summary

SKU: PA1694
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-Somatostatin Receptor 2/SSTR2 Antibody

View all Somatostatin R2/SSTR2 Antibodies

SKU/Catalog Number

PA1694

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Somatostatin Receptor 2/SSTR2 Antibody catalog # PA1694. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Somatostatin Receptor 2/SSTR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1694)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Somatostatin Receptor 2 (184-198aa RSNQWGRSSCTINWP), identical to the related rat and mouse sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1694 is reactive to SSTR2 in Human, Mouse, Rat

Applications

PA1694 is guaranteed for WB Boster Guarantee

Background of Somatostatin R2/SSTR2

SSTR2 (Somatostatin receptor type 2) is a protein that in humans is encoded by the SSTR2 gene. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. Stable SSTR2 transfection of human pancreatic cells, which do not endogenously express SSTR2, inhibits cell proliferation, tumorigenicity, and metastasis. These effects occur as a consequence of an autocrine SSTR2-dependent loop, whereby SSTR2 induces expression of its own ligand, somatostatin.SSTR2 mRNA was variably expressed in all neuroblastoma tumors with a relevant reduction in the more advanced stage.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Rat, Human, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For SSTR2 (Source: Uniprot.org, NCBI)

Uniprot ID

P30874

Gene ID

6752

Gene Name

SSTR2

Full Name

Somatostatin receptor type 2

Weight

41.333kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

Smstr2; Somatostatin R2; somatostatin receptor 2; somatostatin receptor type 2; SomatostatinR2; SRIF-1; SS2R; SS-2-R; SS2-R; SST2; SSTR2 SSTR2 somatostatin receptor 2 somatostatin receptor type 2|SRIF-1|SS2R

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SSTR2, check out the SSTR2 Infographic

SSTR2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SSTR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

PA1694 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Li M, Wang S, Wang S, Zhang L, Wu D, Yang R, Ji A, Li Y, Wang J. Exp Ther Med. 2017 Aug;14(2):1732-1738. doi: 10.3892/etm.2017.4651. Epub 2017 Jun 22. Occludin downregulation in high glucose is regulated by SSTR2 via the VEGF/NRP1/Akt signaling pa...

Guo Rs, Shi Pd, Zhou J, Chen Yy. Asian Pac J Cancer Prev. 2013;14(7):4071-5. Somatostatin Receptors 3, 4 And 5 Play Important Roles In Gallbladder Cancer.

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3 Customer Q&As for Anti-Somatostatin Receptor 2/SSTR2 Antibody

Question

Please see the WB image, lot number and protocol we used for buccal mucosa cell using anti-Somatostatin Receptor 2/SSTR2 antibody PA1694. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2019-08-29

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-08-29

Question

We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for buccal mucosa cell using anti-Somatostatin Receptor 2/SSTR2 antibody PA1694. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2019-06-18

Answer

We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-06-18

Question

We are currently using anti-Somatostatin Receptor 2/SSTR2 antibody PA1694 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on dog tissues as well?

Z. Williams

Verified customer

Asked: 2016-06-22

Answer

The anti-Somatostatin Receptor 2/SSTR2 antibody (PA1694) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2016-06-22

Size

Conjugation

Total: $315

SKU:PA1694

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