Product Info Summary
SKU: | A02151-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-TAF1 Antibody
View all KAT4/TBP Associated Factor 1 Antibodies
SKU/Catalog Number
A02151-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TAF1 Antibody catalog # A02151-2. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TAF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02151-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human TAF1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02151-2 is reactive to TAF1 in Human, Mouse, Rat
Applications
A02151-2 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
212.677kDa
Background of KAT4/TBP Associated Factor 1
Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.
Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).
Ruppert S., Nature 362:175-179(1993).
Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For TAF1 (Source: Uniprot.org, NCBI)
Gene Name
TAF1
Full Name
Transcription initiation factor TFIID subunit 1
Weight
212.677kDa
Superfamily
TAF1 family
Alternative Names
250kDa; BA2Rdystonia 3 (with Parkinsonism); CCG1TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 250kD; CCGS; Cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; DYT3/TAF1; EC 2.7.11; EC 2.7.11.1; KAT4; NSCL2; OF; P250; TAF(II)250; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF2AN-TAF1; TAFII-250; TAFII250DYT3; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide; Transcription initiation factor TFIID 250 kDa subunit; transcription initiation factor TFIID subunit 1; XDP TAF1 BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, MRXS33, N-TAF1, NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP TATA-box binding protein associated factor 1 transcription initiation factor TFIID subunit 1|TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa|TBP-associated factor 250 kDa|cell cycle gene 1 protein|cell cycle, G1 phase defect|complementation of cell cycle block, G1-to-S|transcription factor TFIID p250 polypeptide
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TAF1, check out the TAF1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TAF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TAF1 Antibody (A02151-2)
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No publications found for A02151-2
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