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Product Info Summary
| SKU: | A06806 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-TEM2 RASD2 Antibody
SKU/Catalog Number
A06806
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TEM2 RASD2 Antibody (Catalog # A06806). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TEM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TEM2 RASD2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06806)
Host
Rabbit
Contents
TEM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TEM2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human TEM2. The immunogen is located within the last 50 amino acids of TEM2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of Lipe are known to exist.
Reactive Species
A06806 is reactive to RASD2 in Human, Mouse, Rat
Applications
A06806 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
30.366kDa
Background of RASD2
Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TEM2 antibody can be used for detection of TEM2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TEM2 in human colon tissue lysate with TEM2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of TEM2 in human colon tissue with TEM2 antibody at 2.5 μg/mL.
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Immunofluorescence of TEM2 in Human Colon cells with TEM2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For RASD2 (Source: Uniprot.org, NCBI)
Gene Name
RASD2
Full Name
GTP-binding protein Rhes
Weight
30.366kDa
Superfamily
small GTPase superfamily
Alternative Names
GTP-binding protein Rhes; MGC:4834; RASD family, member 2; Rhes; TEM2Ras homolog enriched in striatum; Tumor endothelial marker 2 RASD2 Rhes, TEM2 RASD family member 2 GTP-binding protein Rhes|Ras homolog enriched in striatum|tumor endothelial marker 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RASD2, check out the RASD2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RASD2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TEM2 RASD2 Antibody (A06806)
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No publications found for A06806
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Customer Reviews
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