Product Info Summary
SKU: | A08466T18 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC |
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Product info
Product Name
Anti-TFIIH p44 (T18) GTF2H2 Antibody
SKU/Catalog Number
A08466T18
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TFIIH p44 (T18) GTF2H2 Antibody catalog # A08466T18. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TFIIH p44 (T18) GTF2H2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08466T18)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human TFIIH p44
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A08466T18 is reactive to GTF2H2 in Human, Mouse, Rat
Applications
A08466T18 is guaranteed for IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
44.419kDa
Background of GTF2H2
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).
Caffrey J.J., FEBS Lett. 442:99-104(1999).
Chi H., Genomics 56:324-336(1999).
Wiemann S., Genome Res. 11:422-435(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of GTF2H2 using Anti-TFIIH p44 (T18) GTF2H2 Antibody (A08466T18).
Immunohistochemistry (IHC) analyzes of TFIIH p44 (T18) pAb in paraffin-embedded human kidney carcinoma tissue at 1:50.showing nucleus staining. Negative control (the right)Using PBS instead of primary antibodyProtein Target Info & Infographic
Gene/Protein Information For GTF2H2 (Source: Uniprot.org, NCBI)
Gene Name
GTF2H2
Full Name
General transcription factor IIH subunit 2
Weight
44.419kDa
Superfamily
GTF2H2 family
Alternative Names
Basic transcription factor 2 44 kDa subunit; BTF2 p44; BTF2; BTF2P44TFIIH basal transcription factor complex p44 subunit; General transcription factor IIH polypeptide 2; general transcription factor IIH subunit 2; general transcription factor IIH, polypeptide 2 (44kD subunit); general transcription factor IIH, polypeptide 2, 44kD subunit; general transcription factor IIH, polypeptide 2, 44kDa; MGC102806; T-BTF2P44; TFIIH GTF2H2 BTF2, BTF2P44, T-BTF2P44, TFIIH, p44 general transcription factor IIH subunit 2 general transcription factor IIH subunit 2|BTF2 p44|TFIIH basal transcription factor complex p44 subunit|basic transcription factor 2 44 kDa subunit|general transcription factor IIH polypeptide 2|general transcription factor IIH, polypeptide 2, 44kD subunit|general transcription factor IIH, polypeptide 2, 44kDa
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GTF2H2, check out the GTF2H2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GTF2H2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TFIIH p44 (T18) GTF2H2 Antibody (A08466T18)
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No publications found for A08466T18
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