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- Table of Contents
THRA Antibodies
AND THRA ELISA kits, THRA Proteins
Many biological assays use antibodies to detect THRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with THRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop THRA antibodies...
Designing a Western blot for THRA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the THRA Western Blot GuideTHRA Infographic by Boster Bio
All THRA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04545-1
100 μg/vial
Cat # A04545-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A01775-3
100 μg/vial
Cat # A01775-3
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05150-1
100 μg/vial
Cat # A05150-1
100 μg/vial
Human
$628
Cat # LS007067
20 µg, 100 µg
Cat # LS007067
20 µg, 100 µg
$1062
Cat # PROTP10827
20 µg
Cat # PROTP10827
20 µg
THRA Overview
Facts about Thyroid hormone receptor alpha.
Thyroid hormone receptor alpha (THRA)
Isoform Alpha-1: Nuclear hormone receptor that can function as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | THRA |
| Uniprot: | P10827 |
| Entrez: | 7067 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
AR7; c-ERBA-1; c-erbA-alpha; EAR7; EAR-7; EAR-7.1/EAR-7.2; ERBA; ERBA1thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog); ERBA-related 7; MGC000261; MGC43240; NR1A 1; NR1A1; NR1A1THRA3; Nuclear receptor subfamily 1 group A member 1; THRA; THRA1ERB-T-1; THRA2; thyroid hormone receptor alpha; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a)oncogene homolog, avian); TR alpha; triiodothyronine receptor; v-ErbA1; V-erbA-related protein 7
Molecular Weight
Mass (kDA):
54.816 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.1 |
| Sequence: | 17; NC_000017.11 (40062193..40093867) |
Subcellular Localizations
Nucleus.; [Isoform Alpha-2]: Cytoplasm. Nucleus. When overexpressed found in the cytoplasm where it colocalizes with TACC1.
Diseases
- Salmonella Infections
- Malignant Neoplasms
- Hypothyroidism
- Neoplasms
- Pituitary Diseases
- Thyroid Hormone Resistance Syndrome
- Thyroid Diseases
- Mammary Neoplasms
- Complete Hearing Loss
- Cell Transformation, Neoplastic
- Fracture Of First Cervical Vertebra
- Yersinia Infections
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- CEP76
- L3MBTL3
- MED1
- Ncoa6
- SYAP1
Pathways
- Translation
- Cell Proliferation
- Cell Cycle
- Sertoli Cell Development
- Sertoli Cell Proliferation
- Brain Development
- Regulation Of Gene Expression
- Virulence
- Cell Maturation
- Cell Development
- Pathogenesis
- Cell Adhesion
- Rna 3'-end Processing
PTMs
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/THRA
bosterbio.com/bosterbio-gene-info-cards/THRA
References
PMID: 1850510 by Laudet V., et al. Genomic organization of the human thyroid hormone receptor alpha (c- erbA-1) gene.
PMID: 2539258 by Miyajima N., et al. Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus.