Anti-TWEAK TNFSF12 Antibody

TWEAK/TNFSF12 antibody

Boster Bio Anti-TWEAK TNFSF12 Antibody (Catalog # A02009-2). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A02009-2
Size: 0.1 mg
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

Product Name

Anti-TWEAK TNFSF12 Antibody

View all TWEAK/TNFSF12 Antibodies

SKU/Catalog Number

A02009-2

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TWEAK TNFSF12 Antibody (Catalog # A02009-2). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

TWEAK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TWEAK TNFSF12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02009-2)

Host

Rabbit

Contents

TWEAK Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

Anti-TWEAK antibody was raised against recombinant human TWEAK protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist; this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.

Reactive Species

A02009-2 is reactive to TNFSF12 in Human, Mouse

Applications

A02009-2 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

27.216kDa

Background of TWEAK/TNFSF12

TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 0.5-4 μg/mL; IHC: 5-10 μg/mL; IF: 20 μg/mL.
Antibody validated: Western Blot in human and mouse samples; Immunohistochemistry in human and mouse samples; Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For TNFSF12 (Source: Uniprot.org, NCBI)

Gene Name

TNFSF12

Full Name

Tumor necrosis factor ligand superfamily member 12

Weight

27.216kDa

Superfamily

tumor necrosis factor family

Alternative Names

APO3 ligand; APO3LMGC20669; DR3LGTWEAKAPO3/DR3 ligand; MGC129581; TNF-related weak inducer of apoptosis; TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; TWEAK TNFSF12 APO3L, DR3LG, TNLG4A, TWEAK TNF superfamily member 12 tumor necrosis factor ligand superfamily member 12|APO3 ligand|APO3/DR3 ligand|TNF-related WEAK inducer of apoptosis|tumor necrosis factor (ligand) superfamily, member 12|tumor necrosis factor ligand 4A|tumor necrosis factor superfamily member 12

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TNFSF12, check out the TNFSF12 Infographic

TNFSF12 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TNFSF12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02009-2-0.1 mg

0.1 mg

$449

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