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Product Info Summary
| SKU: | A12134 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-XK-related protein 8 XKR8 Antibody
SKU/Catalog Number
A12134
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-XK-related protein 8 XKR8 Antibody (Catalog # A12134). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
XKR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-XK-related protein 8 XKR8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12134)
Host
Rabbit
Contents
XKR8 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
XKR8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human XKR8. The immunogen is located within the last 50 amino acids of XKR8.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
XKR8 antibody is human reactive. At least two isoforms are known to exist; this antibody will detect both isoforms.
Reactive Species
A12134 is reactive to XKR8 in Human
Applications
A12134 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
44.655kDa
Background of XKR8
The XK Kell blood group complex subunit-related family member 8 (XKR8) is a member of a family of proteins that promote the phagocytosis of dying cells by altering the phospholipid distribution of the plasma membrane (1). XKR8 is thought to be a “scramblase”, an enzyme that eliminates the asymmetry of phospholipid distribution in the plasma membrane. In apoptotic cells, XKR8 promotes the cell-surface exposure of phosphatidylserine (PtdSer) which serves as a signal for phagocytosis (1,2).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
XKR8 antibody can be used for detection of XKR8 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of XKR8 in human stomach tissue lysate with XKR8 antibody at 1 μg/ml.
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Immunohistochemistry of XKR8 in human stomach tissue with XKR8 antibody at 5 μg/ml.
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Immunofluorescence of XKR8 in human stomach tissue with XKR8 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For XKR8 (Source: Uniprot.org, NCBI)
Gene Name
XKR8
Full Name
XK-related protein 8
Weight
44.655kDa
Superfamily
XK family
Alternative Names
RP11-460I13.3; XKR8 XK, Kell blood group complex subunit-related family, member 8; XRG8 XKR8 XRG8, hXkr8 XK related 8 XK-related protein 8|X Kell blood group precursor-related family, member 8|X-linked Kx blood group related 8|XK, Kell blood group complex subunit-related family, member 8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on XKR8, check out the XKR8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for XKR8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-XK-related protein 8 XKR8 Antibody (A12134)
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No publications found for A12134
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