A4GNT Antibodies

AND A4GNT ELISA kits, A4GNT Proteins

Many biological assays use antibodies to detect A4GNT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with A4GNT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop A4GNT antibodies...

We validate the specificity of these antibodies to A4GNT by testing them on tissues known to express A4GNT positively and negatively. Browse below to find the A4GNT antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: ING4

A4GNT Infographic by Boster Bio

All A4GNT Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-A4GNT Antibody

Western blot analysis of extracts of various cell lines, using A4GNT antibody at 1:1000 dilution

Human

$405
Cat # A13668
100ul

Anti-alpha Gn-T A4GNT Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A13668-1
100ul

Anti-A4GNT Mouse Monoclonal Antibody [Clone ID: OTI2H9]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY A4GNT (Right lane) cDNA for 48 hrs and lysed

Human

IHC, WB

$523
Cat # M13668
100 µl

Anti-A4GNT Mouse Monoclonal Antibody [Clone ID: OTI1F7]

Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-A4GNT monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human)

Dog, Human, Monkey, Mouse, Rat

$523
Cat # M13668-1
100 µl

A4GNT (NM_016161) Human Over-expression Lysate

Human

$628
Cat # LS051146
20 µg, 100 µg

A4GNT Overview

Facts about Alpha-1,4-N-acetylglucosaminyltransferase.

A4GNT 3D structure. Source: alphafold

Alpha-1,4-N-acetylglucosaminyltransferase (A4GNT)

Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans (PubMed:10430883). Necessary for the synthesis of type III mucin which is specially produced in the stomach, duodenum, and pancreatic duct (PubMed:10430883).

May protect against inflammation-associated gastric adenocarcinomas (By similarity). .

Gene Information

Human
Gene Name:	A4GNT
Uniprot:	Q9UNA3
Entrez:	51146

Family

Belongs to:

glycosyltransferase 32 family

Alternative Names

A4GNT; alpha-1,4-N-acetylglucosaminyltransferase; alpha4GnT

Molecular Weight

Mass (kDA):
39.497 kDA

Genomic Context


Human

Location:	3q22.3
Sequence:	3; NC_000003.12 (138123713..138133310, complement)

Tissue Specificity

Detected in stomach and pancreas.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Stomach Neoplasms
Malignant Neoplasm Of Stomach
Malignant Neoplasms
Adenocarcinoma
Cell Transformation, Neoplastic
Adenoma
Nematode Infections
Gastric Adenocarcinoma
Inflammation

Hyperplasia
Pathologic Neovascularization
Trematode Infections

Pathways

Fucosylation

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/A4GNT

References

PMID: 10430883 by Nakayama J., et al. Expression cloning of a human alpha1, 4-N- acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin.