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- Table of Contents
Facts about A disintegrin and metalloproteinase with thrombospondin motifs 8.
Human | |
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Gene Name: | ADAMTS8 |
Uniprot: | Q9UP79 |
Entrez: | 11095 |
Belongs to: |
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No superfamily |
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; ADAMTS8; ADAMTS-8; ADAM-TS8A disintegrin and metalloproteinase with thrombospondin motifs 8; EC 3.4.24; EC 3.4.24.-; EC 3.4.24.14; EC 3.4.24.82; FLJ41712; METH-2; METH2ADAM-TS 8; METH-8
Mass (kDA):
96.46 kDA
Human | |
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Location: | 11q24.3 |
Sequence: | 11; NC_000011.10 (130404923..130428609, complement) |
Highly expressed in adult and fetal lung, lower expression in brain, placenta, heart, stomach and fetal brain and kidney.
Secreted, extracellular space, extracellular matrix.
PMID: 10438512 by Vazquez F., et al. METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.
PMID: 10610729 by Georgiadis K.E., et al. ADAM-TS8, a novel metalloprotease of the ADAM-TS family located on mouse chromosome 9 and human chromosome 11.