Afadin Antibodies

AND AFDN ELISA kits, Afadin Proteins

Many biological assays use antibodies to detect Afadin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Afadin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Afadin antibodies...

We validate the specificity of these antibodies to Afadin by testing them on tissues known to express AFDN positively and negatively. Browse below to find the AFDN antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AFDN Infographic by Boster Bio

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l Afadin (AFDN) (NM_001040000) Human Over-expression Lysate

Human

$960
Cat # LS004301
20 µg, 100 µg

AFDN Overview

Facts about Afadin.

AFDN 3D structure. Source: alphafold

Afadin (AFDN)

Belongs to an adhesion system, probably along with the E-cadherin-catenin system, which plays a part in the business of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein which connects nectin to the actin cytoskeleton.

Gene Information

Human
Gene Name:	AFDN
Uniprot:	P55196
Entrez:	4301

Family

Belongs to:

No superfamily

Alternative Names

Afadin

Molecular Weight

Mass (kDA):
206.804 kDA

Genomic Context


Human

Location:	6q27
Sequence:	6; NC_000006.12 (167826564..167972023)

Subcellular Localizations

Cell junction, adherens junction. Not found at cell-matrix AJs.

Interacting Proteins

DBN1
NECTIN2
SRC

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AFDN

References

PMID: 8242616 by Prasad R., et al. Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation.

PMID: 9679199 by Saito S., et al. Complete genomic structure, DNA polymorphisms, and alternative splicing of the human AF-6 gene.