AF4/FMR2 family member 3 Antibodies

AND AFF3 ELISA kits, AF4/FMR2 family member 3 Proteins

Many biological assays use antibodies to detect AF4/FMR2 family member 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AF4/FMR2 family member 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AF4/FMR2 family member 3 antibodies...

We validate the specificity of these antibodies to AF4/FMR2 family member 3 by testing them on tissues known to express AFF3 positively and negatively. Browse below to find the AFF3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AFF3 Infographic by Boster Bio

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LAF4 (AFF3) (NM_002285) Human Over-expression Lysate

Human

$960
Cat # LS003899
20 µg, 100 µg

AFF3 Overview

Facts about AF4/FMR2 family member 3.

AFF3 3D structure. Source: alphafold

AF4/FMR2 family member 3 (AFF3)

Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double- stranded DNA.

Gene Information

Human
Gene Name:	AFF3
Uniprot:	P51826
Entrez:	3899

Family

Belongs to:

AF4 family

Alternative Names

AF4/FMR2 family, member 3

Molecular Weight

Mass (kDA):
133.503 kDA

Genomic Context


Human

Location:	2q11.2
Sequence:	2; NC_000002.12 (99545419..100142590, complement)

Tissue Specificity

Preferentially expressed in lymphoid tissues, highest levels being found in the thymus.

Subcellular Localizations

Nucleus.

Diseases

Arthritis
Rheumatoid Arthritis
Leukemia
Acute Lymphocytic Leukemia
Diabetes Mellitus, Insulin-dependent
Chromosomal Translocation
Diabetes Mellitus
Autoimmune Reaction
Malignant Neoplasms
Diabetic Nephropathy
Fraxe Syndrome
Arthritis, Psoriatic

Psoriasis
Autoimmune Diseases
Acute Leukemia
Fragile X Syndrome
Cell Transformation, Neoplastic
Kidney Failure, Chronic

Pathways

Pathogenesis
Methylation
Dna Methylation
Translation
Induction Of Apoptosis
Oncogenesis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AFF3

References

PMID: 8555498 by Ma C., et al. LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias.

PMID: 28397838 by Harripaul R., et al. Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.