This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Protein argonaute-1.
Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions that are complementary to bound brief antigene RNAs (agRNAs).
Human | |
---|---|
Gene Name: | AGO1 |
Uniprot: | Q9UL18 |
Entrez: | 26523 |
Belongs to: |
---|
argonaute family |
AGO1Q99; argonaute 1; argonaute1; DKFZp686M13167; eIF2C 1; eIF-2C 1; EIF2C; Eukaryotic translation initiation factor 2C 1; eukaryotic translation initiation factor 2C, 1; GERP95; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo1; protein argonaute-1; Putative RNA-binding protein Q99
Mass (kDA):
97.214 kDA
Human | |
---|---|
Location: | 1p34.3 |
Sequence: | 1; NC_000001.11 (35869808..35930532) |
Cytoplasm, P-body.
The AGO1 marker can be used to fulfill a variety of needs. It has been established that AGO1 is beneficial in the prevention of cancer and assists in the development of tumor cells. There are many different kinds of AGO1 marker, including AGO1 and AGO2. In this article, we will go over each of them. Picoband and AGO2 markers are also located here.
ELISA kits for the detection of Picokine are developed to decrease non-specific binding and increase capture antibody sensitivity. The result is a high sensitivity, single-digit picogram sensitivity and a low background. The Picokine(tm) ELISA kits are optimized for a wide variety of antigens and proteins and have been validated for use with a variety of samples. They are available through Tebubio.
Anti-IFNGR1 Antibody Picoband was utilized in Immunocytochemistry and Flow Cymetry. This antibody reacts with human beings, Rats, and Mice. It binds to the AGO1 antigen in cell membranes and lysates. Ago1 is a protein involved in the growth of cancerous cells. Antibodies to this protein are available in the market.
AGO1 is a key marker in flow cytometry. This is a method that permits particles or cells to be exposed to the flow cytometry process. This antibody is part of Boster's Picoband(tm) catalog and is highly specific to mouse and human AGO1. Its versatility permits users to perform flow cytometry with confidence and it can also be used with other molecular markers, including a variety of protein fusions.
PMID: 10534406 by Koesters R., et al. Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence, genomic organization, localization to chromosomal bands 1p34-p35, and expression.
PMID: 15260970 by Meister G., et al. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.