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- Table of Contents
Facts about Aflatoxin B1 aldehyde reductase member 3.
.
Human | |
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Gene Name: | AKR7A3 |
Uniprot: | O95154 |
Entrez: | 22977 |
Belongs to: |
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aldo/keto reductase family |
AFAR2; AFB1 aldehyde reductase 2; AFB1-AR 2; aflatoxin B1 aldehyde reductase 2; aflatoxin B1 aldehyde reductase member 3; aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
Mass (kDA):
37.206 kDA
Human | |
---|---|
Location: | 1p36.13 |
Sequence: | 1; NC_000001.11 (19274229..19289362, complement) |
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
Cytoplasm.
PMID: 10383892 by Knight L.P., et al. cDNA cloning, expression and activity of a second human aflatoxin B1- metabolizing member of the aldo-keto reductase superfamily, AKR7A3.
PMID: 12879023 by Praml C., et al. Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells.