AKR7A3 Antibodies

AND AKR7A3 ELISA kits, AKR7A3 Proteins

Many biological assays use antibodies to detect AKR7A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKR7A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKR7A3 antibodies...

We validate the specificity of these antibodies to AKR7A3 by testing them on tissues known to express AKR7A3 positively and negatively. Browse below to find the AKR7A3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AKR7A3 Infographic by Boster Bio

All AKR7A3 Products

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Product

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Specificity

Applications

Price

Anti-AKR7A3 Antibody

Western blot analysis of extracts of various cell lines, using AKR7A3 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A10277
100ul

AKR7A3 (NM_012067) Human Recombinant Protein

Coomassie blue staining of purified AKR7A3 protein

$1249
Cat # PROTO95154
20 µg

Anti-AKR7A3 Antibody (N-Term)

Human

$299
Cat # M10277
50 µl

AKR7A3 (NM_012067) Human Over-expression Lysate

Human

$628
Cat # LS022977
20 µg, 100 µg

Anti-AKR7A3 Antibody

Human, Mouse, Rat

ELISA, WB

$370
Cat # A10277-1
100 μl/vial

AKR7A3 Overview

Facts about Aflatoxin B1 aldehyde reductase member 3.

AKR7A3 3D structure. Source: alphafold

Aflatoxin B1 aldehyde reductase member 3 (AKR7A3)

Can lower the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in defense of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Gene Information

Human
Gene Name:	AKR7A3
Uniprot:	O95154
Entrez:	22977

Family

Belongs to:

aldo/keto reductase family

Alternative Names

AFAR2; AFB1 aldehyde reductase 2; AFB1-AR 2; aflatoxin B1 aldehyde reductase 2; aflatoxin B1 aldehyde reductase member 3; aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)

Molecular Weight

Mass (kDA):
37.206 kDA

Genomic Context


Human

Location:	1p36.13
Sequence:	1; NC_000001.11 (19274229..19289362, complement)

Tissue Specificity

Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.

Subcellular Localizations

Cytoplasm.

Diseases

Liver Neoplasms, Experimental
Hepatocarcinogenesis
Neoplasms
Liver Neoplasms
Carcinogenesis
Hepatotoxicity
Drug-induced Liver Injury
Malignant Neoplasms
Inflammation
Precancerous Conditions

Liver Carcinoma
Infectious Mononucleosis
Malignant Neoplasm Of Liver
Carcinoma
Hyperplasia

Interacting Proteins

AKR7A2
TERF2IP

Pathways

Cell Proliferation
Reverse Transcription
Cell Cycle
Response To Glutathione
Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKR7A3

References

PMID: 10383892 by Knight L.P., et al. cDNA cloning, expression and activity of a second human aflatoxin B1- metabolizing member of the aldo-keto reductase superfamily, AKR7A3.

PMID: 12879023 by Praml C., et al. Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells.