- Table of Content
Cleaves tRNA within anticodon loops to generate tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues.
|pancreatic ribonuclease family|
|Sequence:||14; NC_000014.9 (20684177..20694186)|
Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons.
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus. Nucleus, nucleolus. Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (PubMed:12051708).
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