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- Table of Contents
Anosmin-1 Antibodies
AND ANOS1 ELISA kits, Anosmin-1 Proteins
Many biological assays use antibodies to detect Anosmin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Anosmin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Anosmin-1 antibodies...
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ANOS1 Infographic by Boster Bio
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ANOS1 Overview
Facts about Anosmin-1.
Anosmin-1 (ANOS1)
Has a dual branch-promoting and advice activity, which might play an significant role in the patterning of mitral and tufted cell collaterals into the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.
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Gene Information
| Human | |
|---|---|
| Gene Name: | ANOS1 |
| Uniprot: | P23352 |
| Entrez: | 3730 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Adhesion molecule-like X-linked; ADMLXHHA; anosmin-1; KAL; KALIG1; KALIG-1; Kallmann syndrome 1 sequence; Kallmann syndrome interval gene 1; Kallmann syndrome protein; Kallmann syndrome-1 sequence (anosmin-1); KMS
Molecular Weight
Mass (kDA):
76.112 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp22.31 |
| Sequence: | X; NC_000023.11 (8528874..8732137, complement) |
Tissue Specificity
Expressed in the cerebellum (at protein level).
Subcellular Localizations
Cell membrane; Peripheral membrane protein. Secreted. Proteolytic cleavage may release it from the cell surface into the extracellular space.
Diseases
- Kallmann Syndrome
- Hypogonadism
- Hypogonadotropic Hypogonadism
- Anosmia
- Idiopathic Hypogonadotropic Hypogonadism
- Olfaction Disorders
- Hereditary Diseases
- Tissue Adhesions
- Congenital Absence
- Delayed Puberty
- Hypoplasia
- Pituitary Diseases
Interacting Proteins
- FGFR1
Pathways
- Pathogenesis
- Secretion
- Spermatogenesis
- Cell Adhesion
- System Development
- Cell Migration
- Olfactory Bulb Development
- Localization
- Gonadotropin Secretion
- Chemotaxis
- Translation
- Axon Guidance
- Cell Differentiation
PTMs
- Glycosylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANOS1
bosterbio.com/bosterbio-gene-info-cards/ANOS1
References
PMID: 1913827 by Legouis R., et al. The candidate gene for the X-linked Kallmann syndrome encodes a protein related to adhesion molecules.
PMID: 1303284 by del Castillo I., et al. Structure of the X-linked Kallmann syndrome gene and its homologous pseudogene on the Y chromosome.