ARHGEF16 Antibodies

AND ARHGEF16 ELISA kits, ARHGEF16 Proteins

Many biological assays use antibodies to detect ARHGEF16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGEF16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGEF16 antibodies...

We validate the specificity of these antibodies to ARHGEF16 by testing them on tissues known to express ARHGEF16 positively and negatively. Browse below to find the ARHGEF16 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARHGEF16 Infographic by Boster Bio

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ARHGEF16 Overview

Facts about Rho guanine nucleotide exchange factor 16.

ARHGEF16 3D structure. Source: alphafold

Rho guanine nucleotide exchange factor 16 (ARHGEF16)

Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP.
May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2.

May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6. .

Gene Information

Human
Gene Name:	ARHGEF16
Uniprot:	Q5VV41
Entrez:	27237

Family

Belongs to:

No superfamily

Alternative Names

EPHEXIN4; ephexin-4; GEF16; NBRRho guanine exchange factor (GEF) 16; Rho guanine nucleotide exchange factor (GEF) 16; rho guanine nucleotide exchange factor 16

Molecular Weight

Mass (kDA):
80.105 kDA

Genomic Context


Human

Location:	1p36.32
Sequence:	1; NC_000001.11 (3454589..3481115)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Paraganglionic Neoplasm
Malignant Neoplasms
Neoplasms
Melanoma
Glioma
Metaplastic Cell Transformation
Cell Invasion
Cell Transformation, Neoplastic
Neoplasm Metastasis
Skin Neoplasms
Colonic Neoplasms

Malignant Neoplasm Of Skin
Oligodendroglioma
Brain Neoplasms
Hypokinesia
Mammary Neoplasms
Esophageal Neoplasms

Interacting Proteins

DLG1
MAPK1IP1L
TFG
YWHAZ

Pathways

Methylation
Gene Silencing
Anoikis
Dna Methylation
Regulation Of Anoikis

PTMs

Phosphorylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGEF16

References

PMID: 20679435 by Hiramoto-Yamaki N., et al. Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism.

PMID: 21139582 by Oliver A.W., et al. The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42.