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ARMCX3 Antibodies
AND ARMCX3 ELISA kits, ARMCX3 Proteins
Many biological assays use antibodies to detect ARMCX3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARMCX3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARMCX3 antibodies...
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ARMCX3 Infographic by Boster Bio
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ARMCX3 Overview
Facts about Armadillo repeat-containing X-linked protein 3.
Armadillo repeat-containing X-linked protein 3 (ARMCX3)
Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria into the TRAK2- kinesin motor complex via its interaction with Miro and TRAK2.
Mitochondrial dynamics and distribution is controlled through ARMCX3 protein degradation, which can be promoted by PCK and negatively controlled by WNT1. Improves the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.
Gene Information
| Human | |
|---|---|
| Gene Name: | ARMCX3 |
| Uniprot: | Q9UH62 |
| Entrez: | 51566 |
Family
| Belongs to: |
|---|
| eutherian X-chromosome-specific Armcx family |
Alternative Names
ALEX3arm protein lost in epithelial cancers, X chromosome, 3; ARM protein lost in epithelial cancers on chromosome X 3; armadillo repeat containing, X-linked 3; armadillo repeat-containing X-linked protein 3,1200004E24Rik; dJ545K15.2; DKFZp781N1954; KIAA0443; MGC12199; Protein ALEX3
Molecular Weight
Mass (kDA):
42.501 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq22.1 |
| Sequence: | X; NC_000023.11 (101623130..101631910) |
Subcellular Localizations
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus.
Diseases
- Nervousness
- Crest Syndrome
Interacting Proteins
- MAF1
Pathways
- Nuclear Import
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARMCX3
bosterbio.com/bosterbio-gene-info-cards/ARMCX3
References
PMID: 11162520 by Kurochkin I.V., et al. ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.