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- Table of Contents
Facts about Astrotactin-2.
Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5- trisphosphate and inositol-1,3,4,5-tetrakisphosphate, indicating it is recruited to membranes which contain lipids with a phosphoinositide headgroup (Ref.6).
Human | |
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Gene Name: | ASTN2 |
Uniprot: | O75129 |
Entrez: | 23245 |
Belongs to: |
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astrotactin family |
astrotactin 2; bA264C15.1; bA67K19.1; KIAA0634astrotactin-2
Mass (kDA):
148.243 kDA
Human | |
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Location: | 9q33.1 |
Sequence: | 9; NC_000009.12 (116423112..117415057, complement) |
Membrane; Multi-pass membrane protein. Perikaryon. Cytoplasm, cell cortex. Early endosome. Late endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic vesicle. Integral membrane protein not detected at the cell membrane. Detected in cytoplasmic vesicles in the cell cortex, close to the anterior pole of migrating neurons. Detected at the base of the leading process in migrating neurons.
PMID: 9734811 by Ishikawa K., et al. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PMID: 15164053 by Humphray S.J., et al. DNA sequence and analysis of human chromosome 9.