Astrotactin-2 (ASTN2)

Mediates recycling of the neuronal cell adhesion molecule ASTN1 into the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity).

Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5- trisphosphate and inositol-1,3,4,5-tetrakisphosphate, indicating it is recruited to membranes which contain lipids with a phosphoinositide headgroup (Ref.6).