Probable phospholipid-transporting ATPase IF (ATP11B)

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids in the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable).

Involved in regulation of sensitivity to cisplatin; may give rise to secretory vesicle transport of cisplatin from Golgi to plasma membrane. .