Alox8 Antibodies

AND Alox8 ELISA kits, Alox8 Proteins

Many biological assays use antibodies to detect Alox8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alox8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alox8 antibodies...

We validate the specificity of these antibodies to Alox8 by testing them on tissues known to express Alox8 positively and negatively. Browse below to find the Alox8 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: Alox5ap

Alox8 Infographic by Boster Bio

All Alox8 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Alox8 Overview

Facts about Arachidonate 8S-lipoxygenase.

Alox8 3D structure. Source: alphafold

Arachidonate 8S-lipoxygenase (Alox8)

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. From arachidonate mainly produces (8S)-HPETE and in addition, minor products derived from (8S)-HPETE itself that may consist of leukotriene A4 and 8,15-diHPETE.

With arachidonate as substrate, has no detectable 15S-lipoxygenase activity and only displays a 8S-lipoxygenase activity. However, it may have a 15S-lipoxygenase activity with (8S)-HPETE to produce (8S,15S)-diHPETE.

Gene Information

Mouse
Gene Name:	Alox8
Uniprot:	O35936
Entrez:	11688

Family

Belongs to:

lipoxygenase family

Alternative Names

Arachidonate 8S-lipoxygenase

Molecular Weight

Mass (kDA):
76.23 kDA

Genomic Context


Mouse

Location:	11\|11 B3
Sequence:	11;

Tissue Specificity

Expressed in epidermis and brain. No expression found in heart, spleen, liver, skeletal muscle, kidney or testis.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Alox8

References

PMID: 9305900 by Jisaka M., et al. Molecular cloning and functional expression of a phorbol ester- inducible 8S-lipoxygenase from mouse skin.

PMID: 9518531 by Krieg P., et al. cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin.