B3GAT1 Antibodies

AND B3GAT1 ELISA kits, B3GAT1 Proteins

Many biological assays use antibodies to detect B3GAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with B3GAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop B3GAT1 antibodies...

We validate the specificity of these antibodies to B3GAT1 by testing them on tissues known to express B3GAT1 positively and negatively. Browse below to find the B3GAT1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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B3GAT1 Infographic by Boster Bio

All B3GAT1 Products

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Specificity

Applications

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Anti-Hu CD57 Purified B3GAT1 Monoclonal Antibody

Flow cytometry analysis (surface staining) of human buffy coat cells with anti-human CD57 (TB01) purified, GAM-APC

Human

Flow Cytometry, IHC-P, IHC-F, ICC, WB

$299
Cat # M09548-1
0.1 mg

Anti-CD57 (4G2) monoclonal B3GAT1 Antibody

Western blot (WB) analysis of CD57 mAb at 1:500 dilution
Lane1:U-87MG whole cell lysate(40ug)
Lane2:The Brain tissue lysate of Mouse(40ug)
Lane3:The Brain tissue lysate of Rat(40ug)
Lane4:C6 whole cell lysate(40ug)
Lane5:The Heart tissue lysate of Mouse(40ug)

Human, Mouse, Rat

$482
Cat # M09548-2
100ul

Anti-CD57 B3GAT1 Antibody

1 Citations

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A09548
100ul

Human B3GAT1 Recombinant Protein

SDS-PAGE

$287
Cat # PROTQ9P2W7
Starting from 10ug

CD57 (B3GAT1) (NM_018644) Human Over-expression Lysate

CD57 (B3GAT1) Human Over-expression Lysates NM_018644

Human

$628
Cat # LS027087
20 µg, 100 µg

B3GAT1 Overview

Facts about Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1.

B3GAT1 3D structure. Source: alphafold

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (B3GAT1)

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis.

Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the best, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin.

Gene Information

Human
Gene Name:	B3GAT1
Uniprot:	Q9P2W7
Entrez:	27087

Family

Belongs to:

glycosyltransferase 43 family

Alternative Names

B3GAT1; beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P); Beta-1,3-glucuronyltransferase 1; CD57; EC 2.4.1.135; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; GLCATP; GlcAT-P; GLCATPGLCUATP; GLCUATP; glcUAT-P; Glucuronosyltransferase P; HNK1; LEU7; NK1; NK-1; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase

Molecular Weight

Mass (kDA):
38.256 kDA

Genomic Context


Human

Location:	11q25
Sequence:	11; NC_000011.10 (134378504..134412242, complement)

Tissue Specificity

Mainly expressed in the brain.

Subcellular Localizations

[Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.; [Isoform 2]: Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Secreted.

Diseases

Schizophrenia
Tissue Adhesions
Influenza
Rubella
Cleft Palate
Atrophy
Psychotic Disorders
Congenital Anomaly Of Face
Cancer Patients And Suicide And Depression
Cytomegalovirus Infections
Nervousness

Innate Immune Response
Depressive Disorder
Chromosome Breakage
Chromosomal Translocation
Cleft Lip
Dysequilibrium Syndrome

Pathways

Cell Adhesion
Innate Immune Response
Immune Response
Glycosylation
Synaptic Transmission
Larval Development
Virulence

Nuclear Import

PTMs

Glycosylation

Research Areas

Cancer
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/B3GAT1

References

PMID: 10783264 by Mitsumoto Y., et al. Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope.

PMID: 14993226 by Kakuda S., et al. Structural basis for acceptor substrate recognition of a human glucuronyltransferase, GlcAT-P, an enzyme critical in the biosynthesis of the carbohydrate epitope HNK-1.