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Bcl-2-like protein 1 Antibodies
AND BCL2L1 ELISA kits, Bcl-2-like protein 1 Proteins
Many biological assays use antibodies to detect Bcl-2-like protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bcl-2-like protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bcl-2-like protein 1 antibodies...
Designing a Western blot for Bcl-2-like protein 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BCL2L1 Western Blot GuideBCL2L1 Infographic by Boster Bio
All BCL2L1 Products
Product
Figures
Specificity
Applications
Price
Anti-Bcl-XS/BCL2L1 Antibody Picoband®
6 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1232
100 μg/vial
Cat # PA1232
100 μg/vial
Anti-Bcl-XL/BCL2L1 Antibody Picoband®
3 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A00181
100 μg/vial
Cat # A00181
100 μg/vial
Anti-Bim/BCL2L11 Antibody Picoband®
1 Citations
Human, Mouse
Flow Cytometry, IHC, WB
$370
Cat # A01552-4
100 μg/vial
Cat # A01552-4
100 μg/vial
Anti-Bcl-X/BCL2L1 Antibody Picoband®
4 Citations
Human
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9917
100 μg/vial
Cat # PB9917
100 μg/vial
Anti-Bim BCL2L11 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01552
100 μl
Cat # M01552
100 μl
Anti-Bcl-XL BCL2L1 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00181-1
100 μl
Cat # M00181-1
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M09347-1
100 μl/vial
Cat # M09347-1
100 μl/vial
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M00181-3
100 µl/vial
Cat # M00181-3
100 µl/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M14383
100 µl/vial
Cat # M14383
100 µl/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M06508
100 μl/vial
Cat # M06508
100 μl/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00181-4
20μL, 40μL, 100μL, 200μL
Cat # M00181-4
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M01552-1
20μL, 40μL, 100μL, 200μL
Cat # M01552-1
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00181T47-1
100ul
Cat # A00181T47-1
100ul
Human, Mouse, Rat
ELISA, IF, IHC
$380
Cat # A00181T115
100ul
Cat # A00181T115
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC2364
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2364
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2190
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2190
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1057
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1057
1 kit, containing one 96-well plate and all necessary reagents
Human
IHC, WB
$523
Cat # M09347
100 µl
Cat # M09347
100 µl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1061
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1061
1 kit, containing one 96-well plate and all necessary reagents
BCL2L1 Overview
Facts about Bcl-2-like protein 1.
Bcl-2-like protein 1 (BCL2L1)
Potent inhibitor of cell death. Inhibits activation of caspases.
Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also functions as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Gene Information
| Human | |
|---|---|
| Gene Name: | BCL2L1 |
| Uniprot: | Q07817 |
| Entrez: | 598 |
Family
| Belongs to: |
|---|
| Bcl-2 family |
Alternative Names
Apoptosis regulator Bcl-X; bcl2-L-1; BCL2-like 1; bcl-2-like protein 1; BCLXBCL2LBcl-X; BclxL; Bcl-xL; BCL-XL/S; BCLXS; bcl-xS; DKFZp781P2092
Molecular Weight
Mass (kDA):
26.049 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q11.21 |
| Sequence: | 20; NC_000020.11 (31664452..31723963, complement) |
Tissue Specificity
Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Subcellular Localizations
[Isoform Bcl-X(L)]: Mitochondrion inner membrane. Mitochondrion outer membrane. Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner (By similarity). Localizes to the centrosome when phosphorylated at Ser-49.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Leukemia
- Malignant Paraganglionic Neoplasm
- Lymphoma
- Mammary Neoplasms
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Breast
- Myeloid Leukemia
- Adenocarcinoma
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
Interacting Proteins
- BAD
- Bad
- BAK1
- BAX
- BBC3
- Bbc3
- BCL2L11
- BECN1
- BID
- BIK
Pathways
- Cell Death
- Cell Cycle
- Induction Of Apoptosis
- Programmed Cell Death
- Cell Proliferation
- Cell Growth
- Pathogenesis
- Localization
- Cell Cycle Arrest
- Drug Resistance
- Apoptotic Process
- Secretion
- Sensitization
PTMs
- Cleavage
- Phosphorylation
- Dephosphorylation
- Phosphorothioation
- Reduction
- Deamidation
- Ubiquitination
- Acetylation
- Methylation
- Oxidation
Research Areas
- Apoptosis
- Cancer
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCL2L1
bosterbio.com/bosterbio-gene-info-cards/BCL2L1
References
PMID: 8358789 by Boise L.H., et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.
PMID: 9675101 by Ban J., et al. Identification of a human cDNA encoding a novel Bcl-x isoform.
16 Publications of Boster Bcl-2-like protein 1 Antibodies & ELISA Kits
- PubMed ID: 10.3892/or.2016.4625, The role of cofilin-l in vulvar squamous cell carcinoma: A marker of carcinogene...
- PubMed ID: 10.3390/i7020059, Downregulation of the Expression of GLUT1 Plays a Role in Apoptosis Induced by S...
- PubMed ID: 10.1097/FJC.0000000000000371, CYP2J2 Overexpression Increases EETs and Protects Against HFD-Induced Atheroscle...
- PubMed ID: 10.1016/j.transproceed.2006.06.008, Comparison of Rapamycin Versus FK506 on Expression of Cytoprotective Genes in th...
- PubMed ID: 10.1016/j.transproceed.2006.06.007, Conversion From Cyclosporine to Mycophenolate Mofetil Improves Expression of A20...
- PubMed ID: 10.1016/j.phymed.2016.04.001, The natural secolignan peperomin E induces apoptosis of human gastric carcinoma ...
- PubMed ID: 10.1016/j.lfs.2006.12.024, ACTX-8, a cytotoxic l-amino acid oxidase isolated from Agkistrodon acutus snake ...
- PubMed ID: 10.1002/ar.21317, Protective Effect of Quercetin on Cadmium‐Induced Oxidative Toxicity on Germ C...
- PubMed ID: 10.1002/ar.21317, Protective Effect of Quercetin on Cadmium‐Induced Oxidative Toxicity on Germ C...
- PubMed ID: 10.1002/ar.21317, Protective Effect of Quercetin on Cadmium‐Induced Oxidative Toxicity on Germ C...
- PubMed ID: 33382670, Chen H,Sheng H,Zhao Y,Zhu G.Piperine Inhibits Cell Proliferation and Induces Apo...
- PubMed ID: 12439908, Relationship between Egr-1 gene expression and apoptosis in esophageal carcinoma...
- PubMed ID: 28849044, Emodin alleviates severe acute pancreatitis-associated acute lung injury by decr...
- PubMed ID: 28731164, Guo X, Guo N, Zhao J, Cai Y. Oncol Rep. 2017 Sep;38(3):1442-1450. doi: 10.3892/o...
- PubMed ID: 29541349, Liu X, Lin X, Mi Y, Li J, Zhang C. Oxid Med Cell Longev. 2018 Jan 9;2018:9390810...
- PubMed ID: 24213508, Zhou X, Zhang Y, Li Y, Hao X, Liu X, Wang Y. Cancers (Basel). 2012 Dec 4;4(4):13...
*More publications can be found for each product on its corresponding product page