BRSK1 Antibodies

AND BRSK1 ELISA kits, BRSK1 Proteins

Many biological assays use antibodies to detect BRSK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BRSK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BRSK1 antibodies...

We validate the specificity of these antibodies to BRSK1 by testing them on tissues known to express BRSK1 positively and negatively. Browse below to find the BRSK1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BRSK1 Infographic by Boster Bio

All BRSK1 Products

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Specificity

Applications

Price

BRSK1 Colorimetric Cell-Based ELISA

Western blot analysis of extracts from 293 cells

Human, Mouse

ELISA

$480
Cat # EKC1881
1 kit, containing one 96-well plate and all necessary reagents

Anti-BRSK1 Antibody

Western blot analysis of BRSK1 in human brain tissue lysate with BRSK1 antibody at (A) 0

Immunohistochemistry of BRSK1 in human brain tissue with BRSK1 antibody at 2

Immunofluorescence of BRSK1 in Human Brain cells with BRSK1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A05997-1
0.1 mg

Anti-BRSK1 Antibody Picoband®

Western blot analysis of BRSK1 using anti-BRSK1 antibody (A05997-2)

IHC analysis of BRSK1 using anti-BRSK1 antibody (A05997-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05997-2
100 μg/vial

BRSK1 (NM_032430) Human Over-expression Lysate

Human

$960
Cat # LS084446
20 µg, 100 µg

BRSK1 Overview

Facts about Serine/threonine-protein kinase BRSK1.

BRSK1 3D structure. Source: alphafold

Serine/threonine-protein kinase BRSK1 (BRSK1)

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU in'Thr-529' and'Ser-579'.

Also regulates neuron polarization by mediating phosphorylation of WEE1 in'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 action in polarized neurons. In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.

Gene Information

Human
Gene Name:	BRSK1
Uniprot:	Q8TDC3
Entrez:	84446

Family

Belongs to:

protein kinase superfamily

Alternative Names

BR serine/threonine kinase 1; EC 2.7.11; EC 2.7.11.1; FLJ43009; KIAA1811BR serine/threonine-protein kinase 1; protein kinase SAD1A; SAD1 kinase; SAD1; Serine/threonine-protein kinase SAD-B

Molecular Weight

Mass (kDA):
85.087 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (55283997..55312562)

Tissue Specificity

Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, synapse. Cell junction, synapse, presynaptic active zone. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage (By similarity).