Protein BTG2 Antibodies

AND BTG2 ELISA kits, Protein BTG2 Proteins

Many biological assays use antibodies to detect Protein BTG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein BTG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein BTG2 antibodies...

We validate the specificity of these antibodies to Protein BTG2 by testing them on tissues known to express BTG2 positively and negatively. Browse below to find the BTG2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BTG2 Infographic by Boster Bio

All BTG2 Products

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Anti-BTG2 Antibody Picoband®

4 Q&As

Flow Cytometry analysis of A431 cells using anti-BTG2 antibody (A01461-1)

Western blot analysis of BTG2 using anti-BTG2 antibody (A01461-1)

Human

Flow Cytometry, WB

$370
Cat # A01461-1
100 μg/vial

Anti-BTG2 Mouse Monoclonal Antibody [Clone ID: OTI4C10]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BTG2 (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BTG2 mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-BTG2 mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M01461
100 µl

BTG2 (NM_006763) Human Over-expression Lysate

Human

$628
Cat # LS007832
20 µg, 100 µg

BTG2 Overview

Facts about Protein BTG2.

BTG2 3D structure. Source: alphafold

Protein BTG2 (BTG2)

Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent Method.

In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation.

Gene Information

Human
Gene Name:	BTG2
Uniprot:	P78543
Entrez:	7832

Family

Belongs to:

BTG family

Alternative Names

B-cell translocation gene 2; BTG family member 2; BTG family, member 2; MGC126063; MGC126064; NGF-inducible proliferative protein PC3; PC3nerve growth factor-inducible proliferative; pheochromacytoma cell-3; protein BTG2; TIS21

Molecular Weight

Mass (kDA):
17.416 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (203305519..203309602)

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Cell Transformation, Neoplastic
Carcinogenesis
Nervousness
Inflammation
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Prostate
Neoplasm Metastasis
Prostatic Neoplasms

Leukemia
Cell Invasion
Hyperplasia
Growth Arrest
Pheochromocytoma
Liver Carcinoma
Liver Neoplasms

Interacting Proteins

AR
CNOT7
Cnot7
CNOT8

Pathways

Cell Cycle
Cell Proliferation
Neurogenesis
Cell Growth
Cell Differentiation
Cell Cycle Arrest
Cell Death
Methylation
Dna Repair
G1 Phase
Pathogenesis
S Phase
Localization

Regeneration
Cell Division
Translation
Cell Migration
Regulation Of Gene Expression
Mitosis
Protein Methylation

PTMs

Phosphorylation
Methylation
Acetylation
Demethylation

Reduction
Cleavage
Deacetylation
Oxidation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BTG2

References

PMID: 8944033 by Rouault J.-P., et al. Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway.

PMID: 11267995 by Tirone F.; The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?