BHMT2 Antibodies

AND BHMT2 ELISA kits, BHMT2 Proteins

Many biological assays use antibodies to detect BHMT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BHMT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BHMT2 antibodies...

We validate the specificity of these antibodies to BHMT2 by testing them on tissues known to express BHMT2 positively and negatively. Browse below to find the BHMT2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BHMT2 Infographic by Boster Bio

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BHMT2 (NM_017614) Human Recombinant Protein

Coomassie blue staining of purified BHMT2 protein

$1249
Cat # PROTQ9H2M3
20 µg

BHMT2 Overview

Facts about S-methylmethionine--homocysteine S-methyltransferase BHMT2.

BHMT2 3D structure. Source: alphafold

S-methylmethionine--homocysteine S-methyltransferase BHMT2 (BHMT2)

Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor.

Gene Information

Human
Gene Name:	BHMT2
Uniprot:	Q9H2M3
Entrez:	23743

Family

Belongs to:

No superfamily

Alternative Names

betaine-homocysteine methyltransferase 2; betaine--homocysteine S-methyltransferase 2; EC 2.1.1.5; FLJ20001

Molecular Weight

Mass (kDA):
40.354 kDA

Genomic Context


Human

Location:	5q14.1
Sequence:	5; NC_000005.10 (79069767..79090069)

Tissue Specificity

Expressed in liver and kidney and at reduced levels in the brain, heart, and skeletal muscle.

Diseases

5,10-methylenetetrahydrofolate Reductase Deficiency
Cleft Lip
Cleft Palate
Hyperhomocysteinemia
Cerebrovascular Accident
Congenital Abnormality
Cardiovascular Diseases
Vascular Diseases
Cleft Palate With Cleft Lip
Aneurysm
Dyslipidemias
Brain Ischemia
Stenosis

Drug-induced Liver Injury
Craniofacial Abnormalities
Malignant Tumor Of Colon
Myeloid Leukemia, Chronic
Lung Diseases
Infertility
Coronary Artery Disease

Pathways

Methylation
Transport
Cell Division
Protein Targeting
Amino Acid Homeostasis
Pathogenesis

PTMs

Methylation

Reduction

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BHMT2

References

PMID: 11087663 by Chadwick L.H., et al. Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes.

PMID: 18230605 by Szegedi S.S., et al. Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine- homocysteine methyltransferase.