C8G Antibodies

AND C8G ELISA kits, C8G Proteins

Many biological assays use antibodies to detect C8G, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C8G in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C8G antibodies...

We validate the specificity of these antibodies to C8G by testing them on tissues known to express C8G positively and negatively. Browse below to find the C8G antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C8G Infographic by Boster Bio

All C8G Products

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Product

Figures

Specificity

Applications

Price

Anti-CO8G C8G Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08162
100ul

Human C8G Recombinant Protein

SDS-PAGE

$250
Cat # PROTP07360
Starting from 20ug

C8G Overview

Facts about Complement component C8 gamma chain.

C8G 3D structure. Source: alphafold

Complement component C8 gamma chain (C8G)

C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex.

C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol.

Gene Information

Human
Gene Name:	C8G
Uniprot:	P07360
Entrez:	733

Family

Belongs to:

calycin superfamily

Alternative Names

Complement component C8 gamma chain

Molecular Weight

Mass (kDA):
22.277 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (136944870..136946981)

Subcellular Localizations

Secreted.

PTMs

Disulfide bond

Pyrrolidone carboxylic acid

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C8G

References

PMID: 3676249 by Ng S.C., et al. The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes.

PMID: 2447883 by Haefliger J.-A., et al. Structural homology of human complement component C8 gamma and plasma protein HC: identity of the cysteine bond pattern.