CACNA1E Antibodies

AND CACNA1E ELISA kits, CACNA1E Proteins

Many biological assays use antibodies to detect CACNA1E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CACNA1E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CACNA1E antibodies...

We validate the specificity of these antibodies to CACNA1E by testing them on tissues known to express CACNA1E positively and negatively. Browse below to find the CACNA1E antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: BFSP1 Next: CACNA2D1

CACNA1E Infographic by Boster Bio

All CACNA1E Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CACNA1E Antibody (Monoclonal, 31C43)

Mouse, Rat

IHC, WB

$370
Cat # M05359
100 μl/vial

CACNA1E Overview

Facts about Voltage-dependent R-type calcium channel subunit alpha-1E.

CACNA1E 3D structure. Source: alphafold

Voltage-dependent R-type calcium channel subunit alpha-1E (CACNA1E)

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in many different calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP).

Gene Information

Human
Gene Name:	CACNA1E
Uniprot:	Q15878
Entrez:	777

Family

Belongs to:

calcium channel alpha-1 subunit (TC 1.A.1.11) family

Alternative Names

Voltage-dependent R-type calcium channel subunit alpha-1E

Molecular Weight

Mass (kDA):
261.731 kDA

Genomic Context


Human

Location:	1q25.3
Sequence:	1; NC_000001.11 (181317712..181808084)

Tissue Specificity

Expressed in neuronal tissues and in kidney.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Epileptic encephalopathy, early infantile, 69 (EIEE69)

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CACNA1E

References

PMID: 7536609 by Schneider T., et al. Molecular analysis and functional expression of the human type E neuronal Ca2+ channel alpha 1 subunit.

PMID: 8071363 by Williams M.E., et al. Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.