CACNB4 Antibodies

AND CACNB4 ELISA kits, CACNB4 Proteins

Many biological assays use antibodies to detect CACNB4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CACNB4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CACNB4 antibodies...

We validate the specificity of these antibodies to CACNB4 by testing them on tissues known to express CACNB4 positively and negatively. Browse below to find the CACNB4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CACNB4 Infographic by Boster Bio

All CACNB4 Products

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Specificity

Applications

Price

CACNB4 (NM_000726) Human Over-expression Lysate

CACNB4 Human Over-expression Lysates NM_000726

Human

$628
Cat # LS000785
20 µg, 100 µg

Anti-CACB4 CACNB4 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06596
100ul

CACNB4 Overview

Facts about Voltage-dependent L-type calcium channel subunit beta-4.

CACNB4 3D structure. Source: alphafold

Voltage-dependent L-type calcium channel subunit beta-4 (CACNB4)

The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. .

Gene Information

Human
Gene Name:	CACNB4
Uniprot:	O00305
Entrez:	785

Family

Belongs to:

calcium channel beta subunit family

Alternative Names

calcium channel beta-4 subunit; calcium channel, voltage-dependent, beta 4 subunit; EJM; EJM4; EJM6; voltage-dependent L-type calcium channel subunit beta-4

Molecular Weight

Mass (kDA):
58.169 kDA

Genomic Context


Human

Location:	2q23.3
Sequence:	2; NC_000002.12 (151832771..152099167, complement)

Tissue Specificity

Expressed predominantly in the cerebellum and kidney.

Diseases

Epilepsy
Ataxia
Absence Epilepsy
Lethargy
Epilepsies, Myoclonic
Myoclonic Epilepsy, Juvenile
Episodic Ataxia Type 2 (disorder)
Atrophy
Vertigo
Nervous System Disorder
Epilepsy, Generalized

Pain
Cerebellar Ataxia
Neuralgia
Familial Hemiplegic Migraine
Nystagmus
Migraine Disorders

Interacting Proteins

EFHC2
SYT1

Pathways

Localization
Synaptic Transmission
Response To Ischemia
Nucleosome Assembly
Cell Death
Gonadotropin Secretion
Rna Processing
Nuclear Export

Epiboly
Secretion

PTMs

Dephosphorylation

Palmitoylation

Research Areas

Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CACNB4

References

PMID: 9254841 by Taviaux S., et al. Assignment of human genes for beta 2 and beta 4 subunits of voltage- dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23.

PMID: 11880487 by Helton T.D., et al. Alternative splicing of the beta 4 subunit has alpha 1 subunit subtype-specific effects on Ca2+ channel gating.