CACNG4 Antibodies

AND CACNG4 ELISA kits, CACNG4 Proteins

Many biological assays use antibodies to detect CACNG4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CACNG4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CACNG4 antibodies...

We validate the specificity of these antibodies to CACNG4 by testing them on tissues known to express CACNG4 positively and negatively. Browse below to find the CACNG4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CACNG4 Infographic by Boster Bio

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CACNG4 (NM_014405) Human Over-expression Lysate

Human

$628
Cat # LS027092
20 µg, 100 µg

CACNG4 Overview

Facts about Voltage-dependent calcium channel gamma-4 subunit.

CACNG4 3D structure. Source: alphafold

Voltage-dependent calcium channel gamma-4 subunit (CACNG4)

Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed:21127204). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4.

Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization (PubMed:21172611). .

Gene Information

Human
Gene Name:	CACNG4
Uniprot:	Q9UBN1
Entrez:	27092

Family

Belongs to:

PMP-22/EMP/MP20 family

Alternative Names

calcium channel, voltage-dependent, gamma subunit 4; MGC11138; MGC24983; neuronal voltage-gated calcium channel gamma-4 subunit; TARP gamma-4; transmembrane AMPAR regulatory protein gamma-4; voltage-dependent calcium channel gamma-4 subunit

Molecular Weight

Mass (kDA):
36.579 kDA

Genomic Context


Human

Location:	17q24.2
Sequence:	17; NC_000017.11 (66964707..67033398)

Tissue Specificity

Detected in heart left ventricle.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Glioblastoma Multiforme
Chromosomal Duplication
Malignant Neoplasm Of Breast
Gait Ataxia
Ataxia
Glioblastoma
Absence Epilepsy
Crest Syndrome
Carcinogenesis

Malignant Neoplasms
Mammary Neoplasms
Chimera Disorder

Pathways

Methylation
Synaptic Transmission

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CACNG4

References

PMID: 10613843 by Burgess D.L., et al. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.

PMID: 21172611 by Kato A.S., et al. Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.