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Calcitonin receptor Antibodies
AND CALCR ELISA kits, Calcitonin receptor Proteins
Many biological assays use antibodies to detect Calcitonin receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calcitonin receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calcitonin receptor antibodies...
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CALCR Overview
Facts about Calcitonin receptor.
Calcitonin receptor (CALCR)
This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CALCR |
| Uniprot: | P30988 |
| Entrez: | 799 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 2 family |
Alternative Names
Calcitonin R; calcitonin receptor; CalcitoninR; CALCR; CRT; CTR; CT-R; CTR1
Molecular Weight
Mass (kDA):
55.329 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.3 |
| Sequence: | 7; NC_000007.14 (93424486..93574730, complement) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Osteoporosis
- Osteopenia
- Cystic Fibrosis
- Fracture
- Fibrosis
- Inflammation
- Cholangiocarcinoma
- Nervousness
- 5,10-methylenetetrahydrofolate Reductase Deficiency
- Dysequilibrium Syndrome
- Hereditary Diseases
- Osteoporotic Fractures
- Metabolic Bone Disorder
Pathways
- Bone Resorption
- Locomotion
- Osteoclast Differentiation
- Aging
- Immune Response
- Menopause
- Complement Activation
- Osteoblast Proliferation
- Endocytosis
- Metaphase
- Insemination
- Leukocyte Activation
- Myeloid Cell Differentiation
PTMs
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CALCR
bosterbio.com/bosterbio-gene-info-cards/CALCR
References
PMID: 1331173 by Gorn A.H., et al. Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line.
PMID: 8078488 by Kuestner R.E., et al. Cloning and characterization of an abundant subtype of the human calcitonin receptor.