CAMSAP2 Antibodies

AND CAMSAP2 ELISA kits, CAMSAP2 Proteins

Many biological assays use antibodies to detect CAMSAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAMSAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAMSAP2 antibodies...

We validate the specificity of these antibodies to CAMSAP2 by testing them on tissues known to express CAMSAP2 positively and negatively. Browse below to find the CAMSAP2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CAMSAP2 Infographic by Boster Bio

All CAMSAP2 Products

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Anti-CAMSAP2 Antibody

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A02887
100 μl/vial

CAMSAP2 Overview

Facts about Calmodulin-regulated spectrin-associated protein 2.

CAMSAP2 3D structure. Source: alphafold

Calmodulin-regulated spectrin-associated protein 2 (CAMSAP2)

Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:23169647, PubMed:24486153, PubMed:24706919). Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization (PubMed:24486153, PubMed:24706919).

Acts on free microtubule minus-ends that aren't capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In addition, it also decreases the speed of microtubule polymerization (PubMed:24486153, PubMed:24706919).

Gene Information

Human
Gene Name:	CAMSAP2
Uniprot:	Q08AD1
Entrez:	23271

Family

Belongs to:

CAMSAP1 family

Alternative Names

calmodulin regulated spectrin-associated protein 1-like 1; calmodulin-regulated spectrin-associated protein 2; CAMSAP2; KIAA1078Calmodulin-regulated spectrin-associated protein 1-like protein 1; MGC150680; MGC150681

Molecular Weight

Mass (kDA):
168.089 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (200738905..200860707)

Subcellular Localizations

Cytoplasm, cytoskeleton. Golgi apparatus. Associated with the minus-end of microtubules and also detected at the centrosomes (PubMed:23169647, PubMed:24486153, PubMed:24908486, PubMed:24706919, PubMed:27666745, PubMed:28814570). Decorates the minus-end of microtubules by decreasing the rate of tubulin incorporation and remaining bound (PubMed:24486153). The length of CAMSAP2-decorated stretches on the minus-end of microtubules depends on MAPRE1/EB1 and MAPRE3/EB3, which promote elongation of CAMSAP2-decorated microtubule stretches (PubMed:28814570). Recruited to the Golgi apparatus by AKAP9 an

Interacting Proteins

EEF1D

Pathways

Organelle Assembly

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAMSAP2

References

PMID: 22116939 by Guo Y., et al. Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese.

PMID: 23169647 by Tanaka N., et al. Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules.