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Calpain-10 Antibodies

AND CAPN10 ELISA kits, Calpain-10 Proteins

Many biological assays use antibodies to detect Calpain-10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calpain-10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calpain-10 antibodies...

We validate the specificity of these antibodies to Calpain-10 by testing them on tissues known to express CAPN10 positively and negatively. Browse below to find the CAPN10 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CAPN10 Infographic by Boster Bio

CAPN10 protein infographic

All CAPN10 Products

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Anti-Calpain 10 CAPN10 Antibody

4 Q&As

Western Blot analysis of LOVO cells using Calpain 10 Polyclonal Antibody

Western Blot analysis of LOVO cells using Calpain 10 Polyclonal Antibody

Human, Mouse, Rat

ELISA, WB

$399
Cat # A03289
100μl

Calpain 10 (CAPN10) (NM_023083) Human Over-expression Lysate

Calpain 10 (CAPN10) Human Over-expression Lysates NM_023083

Calpain 10 (CAPN10) Human Over-expression Lysates NM_023083

Human

$628
Cat # LS011132
20 µg, 100 µg

CAPN10 Overview

Facts about Calpain-10.

CAPN10 3D structure

CAPN10 3D structure. Source: alphafold

Calpain-10 (CAPN10)

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated sugar uptake.

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Gene Information

Human
Gene Name:	CAPN10
Uniprot:	Q9HC96
Entrez:	11132

Gene Information

Family

Belongs to:

peptidase C2 family

Family

Alternative Names

Calcium-activated neutral proteinase 10; calpain 10; calpain-10; calpain-like protease CAPN10; CANP 10; CANP10; EC 3.4.22.-; KIAA1845; NIDDM1

Molecular Weight

Mass (kDA):
74.952 kDA

Molecular Weight

Genomic Context


Human

Location:	2q37.3
Sequence:	2; NC_000002.12 (240586734..240599104)

Tissue Specificity

Detected in primary skeletal muscle cells (at protein level). Ubiquitous.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Dysequilibrium Syndrome
Polycystic Ovary Syndrome
Obesity
Insulin Sensitivity
Impaired Glucose Tolerance
Malignant Neoplasms
Hypertensive Disease
Atherosclerosis
Cardiovascular Diseases

Metabolic Syndrome X
Metabolic Diseases
Cholangiocarcinoma
Arteriosclerosis
Endocrine System Diseases
Carcinoma
Idiopathic Hirsutism

Disease

Pathways

Insulin Secretion
Secretion
Pathogenesis
Proteolysis
Glucose Homeostasis
Exocytosis
Cell Adhesion
Cell Migration
Immune Response
Pigmentation

Mrna Splicing
Translation
Cell Growth
Mating
Autophagy

Pathways

PTMs

Phosphorylation

Reduction

Oxidation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPN10

References

PMID: 11017071 by Horikawa Y., et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.

PMID: 16721485 by Kang E.S., et al. A novel 111/121 diplotype in the Calpain-10 gene is associated with type 2 diabetes.