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- Table of Contents
Facts about Caspase recruitment domain-containing protein 10.
Activates NF-kappa-B via BCL10 and IKK.
.| Human | |
|---|---|
| Gene Name: | CARD10 |
| Uniprot: | Q9BWT7 |
| Entrez: | 29775 |

| Belongs to: |
|---|
| No superfamily |

CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; Carma 3; CARMA3BIMP1Bcl10 binding protein and activator of NFKB; caspase recruitment domain family, member 10; caspase recruitment domain-containing protein 10; MGC142219
Mass (kDA):
115.931 kDA

| Human | |
|---|---|
| Location: | 22q13.1 |
| Sequence: | 22; NC_000022.11 (37490362..37519415, complement) |
Detected in adult heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidney.
Cytoplasm.





PMID: 11259443 by Wang L., et al. CARD10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with Bcl10 and activates NF-kappa B.
PMID: 11356195 by Gaide O., et al. Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation.