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- Table of Contents
Calpastatin Antibodies
AND CAST ELISA kits, Calpastatin Proteins
Many biological assays use antibodies to detect Calpastatin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calpastatin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calpastatin antibodies...
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CAST Infographic by Boster Bio
All CAST Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00337
100 μg/vial
Cat # A00337
100 μg/vial
Human
$960
Cat # LS000831
20 µg, 100 µg
Cat # LS000831
20 µg, 100 µg
CAST Overview
Facts about Calpastatin.
Calpastatin (CAST)
Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a crucial role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CAST |
| Uniprot: | P20810 |
| Entrez: | 831 |
Family
| Belongs to: |
|---|
| protease inhibitor I27 (calpastatin) family |
Alternative Names
BS-17; Calpain inhibitor; calpastatin; MGC9402; Sperm BS-17 component
Molecular Weight
Mass (kDA):
76.573 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q15 |
| Sequence: | 5; NC_000005.10 (96662037..96774683) |
Diseases
- Cardiac Arrhythmia
- Fracture
- Myocardial Infarction
- Infarction
- Tachycardia, Ventricular
- Sudden Cardiac Death
- Allergy
- Cardiac Fibrillation
- Heart Diseases
- Kidney Diseases
- Premature Ventricular Contractions
- Sudden Death
- Heart Failure
Interacting Proteins
- NCK1
Pathways
- Aging
- Localization
- Secretion
- Sensitization
- Hypersensitivity
- Pathogenesis
- Basophil Activation
- Anaphylaxis
- Proteolysis
- Exocytosis
- Translation
- Muscle Atrophy
- Transport
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Reduction
- Methylation
Research Areas
- Hypoxia
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAST
bosterbio.com/bosterbio-gene-info-cards/CAST
References
PMID: 2577276 by Asada K., et al. cDNA cloning of human calpastatin: sequence homology among human, pig, and rabbit calpastatins.
PMID: 11978196 by Zhu H., et al. Cloning and characterization of a novel isoform of calpastatin in human adult testis.