Protein chibby homolog 1 (CBY1)

Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a part in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins.

Promotes adipocyte and cardiomyocyte differentiation. .