Ccdc39 Antibodies

AND Ccdc39 ELISA kits, Ccdc39 Proteins

Many biological assays use antibodies to detect Ccdc39, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ccdc39 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ccdc39 antibodies...

We validate the specificity of these antibodies to Ccdc39 by testing them on tissues known to express Ccdc39 positively and negatively. Browse below to find the Ccdc39 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ccdc39 Infographic by Boster Bio

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CCDC39 (NM_181426) Human Over-expression Lysate

Human

$960
Cat # LS339829
20 µg, 100 µg

Ccdc39 Overview

Facts about Coiled-coil domain-containing protein 39.

Coiled-coil domain-containing protein 39 (Ccdc39)

Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler which determines the 96 nanometer (nm) repeat length and arrangements of elements in cilia and flagella.

Not required for outer dynein arm complexes assembly. .

Gene Information

Mouse
Gene Name:	Ccdc39
Uniprot:	Q9D5Y1
Entrez:	51938

Family

Belongs to:

CCDC39 family

Alternative Names

coiled-coil domain containing 39

Molecular Weight

Mass (kDA):
110.072 kDA

Genomic Context


Mouse

Location:	3\|3 A3
Sequence:	3;

Tissue Specificity

Strongly expressed in tissues rich in ciliated cells. Expressed in olfactory and vomeronasal sensory neurons and the respiratory epithelium. Expressed in node cells carrying motile cilia, in upper and lower airways, and in ependymal and choroid plexus cells.

Diseases

Ciliary Motility Disorders
Dyskinetic Syndrome
Infective Disorder
Kartagener Syndrome
Situs Inversus
Nasal Polyps
Signs And Symptoms, Respiratory
Situs Ambiguus
Otitis Media
Bronchiectasis
Respiration Disorders
Infertility

Respiratory Distress
Respiratory System Abnormalities
Congenital Heart Defects
Congenital Heart Disease
Heart Diseases
Heterotaxy Syndrome

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ccdc39

References

PMID: 21131972 by Merveille A.C., et al. CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs.