Cyclin-F Antibodies

AND CCNF ELISA kits, Cyclin-F Proteins

Many biological assays use antibodies to detect Cyclin-F, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cyclin-F in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cyclin-F antibodies...

We validate the specificity of these antibodies to Cyclin-F by testing them on tissues known to express CCNF positively and negatively. Browse below to find the CCNF antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCNF Infographic by Boster Bio

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Cyclin F (CCNF) (NM_001761) Human Over-expression Lysate

Human

$628
Cat # LS000899
20 µg, 100 µg

CCNF Overview

Facts about Cyclin-F.

CCNF 3D structure. Source: alphafold

Cyclin-F (CCNF)

Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. .

Gene Information

Human
Gene Name:	CCNF
Uniprot:	P41002
Entrez:	899

Family

Belongs to:

cyclin family

Alternative Names

cyclin F; cyclin-F; FBX1FBXO1F-box only protein 1; G2/mitotic-specific cyclin-F

Molecular Weight

Mass (kDA):
87.64 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (2429447..2458854)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Localization in the centrosome is rare in S phase cells and increases in G2 cells, Localizes on both the mother and daughter centrioles. Localization to centrosomes is not dependent on CP110. Also localizes to the nucleus.