CD3EAP Antibodies

AND CD3EAP ELISA kits, CD3EAP Proteins

Many biological assays use antibodies to detect CD3EAP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD3EAP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD3EAP antibodies...

We validate the specificity of these antibodies to CD3EAP by testing them on tissues known to express CD3EAP positively and negatively. Browse below to find the CD3EAP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD3EAP Infographic by Boster Bio

All CD3EAP Products

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Applications

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Anti-CD3EAP/Paf49 Antibody

1 Q&As

Immunohistochemical analysis of paraffin-embedded human tonsil

Western Blot analysis of A549 cells using CD3EAP Polyclonal Antibody

Western blot analysis of lysates from A549 cells, using CD3EAP Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A30649
100ul

Anti-CD3EAP (E474) Antibody

Immunohistochemistry (IHC) analyzes of CD3EAP (E474) pAb in paraffin-embedded human breast carcinoma tissue at 1:100

Human, Mouse, Rat

IHC

$405
Cat # A05591
100ul

Anti-CD3EAP Antibody

Western blot analysis of extracts of various cell lines, using CD3EAP antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A05591-1
100ul

CD3EAP Overview

Facts about DNA-directed RNA polymerase I subunit RPA34.

CD3EAP 3D structure. Source: alphafold

DNA-directed RNA polymerase I subunit RPA34 (CD3EAP)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I synthesizes ribosomal RNA precursors.

Isoform 1 is involved in UBTF-activated transcription, presumably at a step after PIC formation. .

Gene Information

Human
Gene Name:	CD3EAP
Uniprot:	O15446
Entrez:	10849

Family

Belongs to:

eukaryotic RPA34 RNA polymerase subunit family

Alternative Names

A34.5; antisense to ERCC 1; Antisense to ERCC-1 protein; ASE-1ASE1; CASTMGC118851; CD3 epsilon associated protein; CD3e antigen, epsilon polypeptide associated protein; CD3e molecule, epsilon associated protein; CD3E-associated protein; CD3-epsilon-associated protein; DNA-directed RNA polymerase I subunit RPA34; PAF49RNA polymerase I-associated factor PAF49

Molecular Weight

Mass (kDA):
54.986 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45406644..45410766)

Subcellular Localizations

Nucleus, nucleolus. Chromosome. Found at the fibrillar centers of the nucleolus in interphase and during cell division it is localized to the nucleolus organizer regions of the chromosomes.

Diseases

Malignant Neoplasms
Neoplasms
Multiple Myeloma
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Lung
Tumor Progression
Carcinoma
Lupus Erythematosus, Systemic
Colorectal Cancer
Lung Neoplasms
Autoimmune Reaction
Colorectal Neoplasms
Basal Cell Carcinoma

Pyoderma Gangrenosum
Sclerosis
Adenoma
Inflammatory Bowel Diseases
Refractory Chronic Lymphocytic Leukemia
Pyoderma
Intestinal Diseases

Pathways

Dna Repair
Translation
Cell Activation
Cell Proliferation
T Cell Activation
Immune Response
Cell Division
Flight
Chemotaxis
Cell Cycle

Interphase
Interleukin-2 Production
Exocytosis
Lymphocyte Activation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD3EAP

References

PMID: 9426281 by Whitehead C.M., et al. ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes.

PMID: 10373416 by Yamazaki T., et al. CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells.