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- Table of Contents
CD79A Antibodies
AND CD79A ELISA kits, CD79A Proteins
Many biological assays use antibodies to detect CD79A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD79A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD79A antibodies...
Designing a Western blot for CD79A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD79A Western Blot GuideCD79A Infographic by Boster Bio
All CD79A Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01047-1
100 μg/vial
Cat # A01047-1
100 μg/vial
Chicken, Cow, Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat, Primate, Horse
Flow Cytometry, IP, IHC-P, WB
$301
Cat # M01047-4
0.1 mg
Cat # M01047-4
0.1 mg
CD79A Overview
Facts about B-cell antigen receptor complex-associated protein alpha chain.
B-cell antigen receptor complex-associated protein alpha chain (CD79A)
Required in cooperation with CD79B for initiation of the signal transduction cascade triggered by binding of antigen to the B-cell antigen receptor complex (BCR) which contributes to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.
Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK.
Gene Information
| Human | |
|---|---|
| Gene Name: | CD79A |
| Uniprot: | P11912 |
| Entrez: | 973 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD79A antigen (immunoglobulin-associated alpha); CD79a antigen; CD79a molecule, immunoglobulin-associated alpha; CD79A; IGAB-cell antigen receptor complex-associated protein alpha chain; ig-alpha; MB-1 membrane glycoprotein; MB1; MB-1; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein
Molecular Weight
Mass (kDA):
25.038 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.2 |
| Sequence: | 19; NC_000019.10 (41877279..41881372) |
Tissue Specificity
B-cells.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Diseases
- Lymphoma
- Neoplasms
- B-cell Lymphomas
- Leukemia
- Diffuse Large B-cell Lymphoma
- Malignant Paraganglionic Neoplasm
- Acute Lymphocytic Leukemia
- Malignant Neoplasms
- T-cell Lymphoma
- Dog Diseases
- Hodgkin Disease
- Lymphoma, Non-hodgkin
Interacting Proteins
- FATE1
- SLC13A4
- SLC38A1
Pathways
- Cell Development
- Pathogenesis
- Cell Differentiation
- B Cell Differentiation
- Localization
- Cell Activation
- Transport
- Immune Response
- Secretion
- Cell Proliferation
- B Cell Activation
- Reverse Transcription
- Cell Maturation
PTMs
- Phosphorylation
- Glycosylation
- Methylation
Research Areas
- Adaptive Immunity
- Cell Biology
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD79A
bosterbio.com/bosterbio-gene-info-cards/CD79A
References
PMID: 1395095 by Leduc I., et al. Structure and expression of the mb-1 transcript in human lymphoid cells.
PMID: 1534761 by Mueller B.S., et al. Cloning and sequencing of the cDNA encoding the human homologue of the murine immunoglobulin-associated protein B29.