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- Table of Contents
Hsp90 co-chaperone Cdc37 Antibodies
AND CDC37 ELISA kits, Hsp90 co-chaperone Cdc37 Proteins
Many biological assays use antibodies to detect Hsp90 co-chaperone Cdc37, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hsp90 co-chaperone Cdc37 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hsp90 co-chaperone Cdc37 antibodies...
Designing a Western blot for Hsp90 co-chaperone Cdc37? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDC37 Western Blot GuideCDC37 Infographic by Boster Bio
All CDC37 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$370
Cat # M02169
100 μl
Cat # M02169
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M02169-2
20μL, 40μL, 100μL, 200μL
Cat # M02169-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$405
Cat # A02169-1
100ul
Cat # A02169-1
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC2294
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2294
1 kit, containing two 96-well plates and all necessary reagents
CDC37 Overview
Facts about Hsp90 co-chaperone Cdc37.
Hsp90 co-chaperone Cdc37 (CDC37)
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of the activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC37 |
| Uniprot: | Q16543 |
| Entrez: | 11140 |
Family
| Belongs to: |
|---|
| CDC37 family |
Alternative Names
CDC37 (cell division cycle 37, S. cerevisiae, homolog); CDC37 cell division cycle 37 homolog (S. cerevisiae); CDC37 cell division cycle 37 homolog; CDC37A; cell division cycle 37 homolog (S. cerevisiae); Hsp90 chaperone protein kinase-targeting subunit; hsp90 co-chaperone Cdc37; P50CDC37
Molecular Weight
Mass (kDA):
44.468 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.2 |
| Sequence: | 19; NC_000019.10 (10391128..10403568, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Leukemia
- Malignant Paraganglionic Neoplasm
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Breast
- Carcinoma
- Melanoma
- Liver Carcinoma
- Prostatic Neoplasms
- Malignant Neoplasm Of Pancreas
- Malignant Neoplasm Of Prostate
Interacting Proteins
- AKT1
- AKT3
- APOE
- AURKB
- CDK15
- CDK4
- CDK6
- CDK9
- CHUK
- CUL4B
Pathways
- Cell Cycle
- Cell Division
- Cell Proliferation
- Protein Folding
- Cell Growth
- Localization
- Pathogenesis
- Translation
- G1 Phase
- Cell Death
- Mitosis
- Rna Interference
- Autophagy
PTMs
- Phosphorylation
- Cleavage
- Ubiquitination
Research Areas
- Cell Cycle and Replication
- Membrane Trafficking and Chaperones
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC37
bosterbio.com/bosterbio-gene-info-cards/CDC37
References
PMID: 8666233 by Stepanova L., et al. Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4.
PMID: 8703009 by Dai K., et al. Physical interaction of mammalian CDC37 with CDK4.
4 Publications of Boster Hsp90 co-chaperone Cdc37 Antibodies & ELISA Kits
- PubMed ID: 24368518, The Effect of 5?-Adenylic Acid on Hepatic Proteome of Mice Radiated by 60Co ?-ra...
- PubMed ID: 29404146, Serum Heat Shock Protein Levels and the Relationship of Heat Shock Proteins with...
- PubMed ID: 21346199, Jiang Q, Wang Y, Li T, Shi K, Li Z, Ma Y, Li F, Luo H, Yang Y, Xu C. Mol Biol Ce...
- PubMed ID: 23919426, Zhao Z, Miao Y, Pan P, Cheng B, Bai G, Wu H. Bmc Complement Altern Med. 2013 Aug...
*More publications can be found for each product on its corresponding product page