Cat eye syndrome critical region protein 2 (CECR2)

Chromatin reader part of histone-modifying complexes, like the CERF (CECR2-containing-remodeling factor) complex and ISWI-type complicated (PubMed:15640247, PubMed:26365797, PubMed:22464331). It thereby plays a role in a variety of processes during development: required during embryogenesis for neural tube closure and inner ear development.

In adults, required for spermatogenesis, through the formation of ISWI-type chromatin complexes (By similarity). In histone-modifying complexes, CECR2 recognizes and binds acylated histones: binds histones which are acetylated and/or butyrylated (PubMed:26365797, PubMed:22464331).